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And most importantly who is most likely to benefit from them

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The presence or absence of nausea, vomiting, or diarrhea does not determine weight loss success, and the medication remains highly effective even in users who experience minimal to no gastrointestinal symptoms

After four years, the increase in plaque volume was significantly greater in women taking the placebo (+53.1%) than in women taking the garlic supplement (-4.6%), while no significant difference in plaque volume was found between garlic (+1.1%) and placebo (+5.5%) in men (94, 95)